Article

Mendelian imputation of parental genotypes for genome-wide estimation of direct and indirect genetic effects

2020-07-03

Abstract excerpt

Associations between genotype and phenotype derive from four sources: direct genetic effects, indirect genetic effects from relatives, population stratification, and correlations with other variants affecting the phenotype through assortative mating. Genome-wide association studies (GWAS) of unrelated individuals have limited ability to distinguish the different sources of genotype-phenotype association, confusing...

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Literature Corpus work: c4aabcce-6381-563d-a63e-ab0913db5c7e
DOI: 10.1101/2020.07.02.185199

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