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Article

Common SNPs explain a large proportion of the heritability for human height.

Nature genetics - 1 Jul 2010

Yang Jian, Benyamin Beben, McEvoy Brian P, Gordon Scott, Henders Anjali K, Nyholt Dale R, Madden Pamela A, Heath Andrew C, Martin Nicholas G, Montgomery Grant W, Goddard Michael E, Visscher Peter M

Abstract excerpt

SNPs discovered by genome-wide association studies (GWASs) account for only a small fraction of the genetic variation of complex traits in human populations. Where is the remaining heritability? We estimated the proportion of variance for human height explained by 294,831 SNPs genotyped on 3,925 unrelated individuals using a linear model analysis, and validated the estimation method with simulations based on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20562875
DOI: 10.1038/ng.608
PMCID: PMC3232052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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