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Article

An assessment of the individual and collective effects of variants on height using twins and a developmentally informative study design.

PLoS genetics - 1 Dec 2011

Vrieze Scott I, McGue Matt, Miller Michael B, Legrand Lisa N, Schork Nicholas J, Iacono William G

Abstract excerpt

In a sample of 3,187 twins and 3,294 of their parents, we sought to investigate association of both individual variants and a genotype-based height score involving 176 of the 180 common genetic variants with adult height identified recently by the GIANT consortium. First, longitudinal observations on height spanning pre-adolescence through adulthood in the twin sample allowed us to investigate the separate...

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Identifiers

PMID: 22174699
DOI: 10.1371/journal.pgen.1002413
PMCID: PMC3234218

Genes

LIN28B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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