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Article

Lack of Artemisinin Resistance in Plasmodium falciparum in Uganda Based on Parasitological and Molecular Assays.

Antimicrobial agents and chemotherapy - 1 Aug 2015

Cooper Roland A, Conrad Melissa D, Watson Quentin D, Huezo Stephanie J, Ninsiima Harriet, Tumwebaze Patrick, Nsobya Samuel L, Rosenthal Philip J

Abstract excerpt

We evaluated markers of artemisinin resistance in Plasmodium falciparum isolated in Kampala in 2014. By standard in vitro assays, all isolates were highly sensitive to dihydroartemisinin (DHA). By the ring-stage survival assay, after a 6-h DHA pulse, parasitemia was undetectable in 40 of 43 cultures at 72 h. Two of 53 isolates had nonsynonymous K13-propeller gene polymorphisms but did not have the mutations...

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Identifiers

PMID: 26033725
DOI: 10.1128/AAC.00921-15
PMCID: PMC4505276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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