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Article

Evidence of Artemisinin-Resistant Malaria in Africa.

The New England journal of medicine - 23 Sept 2021

Balikagala Betty, Fukuda Naoyuki, Ikeda Mie, Katuro Osbert T, Tachibana Shin-Ichiro, Yamauchi Masato, Opio Walter, Emoto Sakurako, Anywar Denis A, Kimura Eisaku, Palacpac Nirianne M Q, Odongo-Aginya Emmanuel I, Ogwang Martin, Horii Toshihiro, Mita Toshihiro

Abstract excerpt

BACKGROUND: In the six Southeast Asian countries that make up the Greater Mekong Subregion, Plasmodium falciparum has developed resistance to derivatives of artemisinin, the main component of first-line treatments for malaria. Clinical resistance to artemisinin monotherapy in other global regions, including Africa, would be problematic. METHODS: In this longitudinal study conducted in Northern Uganda, we treated...

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Identifiers

PMID: 34551228
DOI: 10.1056/NEJMoa2101746

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