Article
Absence of Plasmodium falciparum artemisinin resistance gene mutations eleven years after the adoption of artemisinin-based combination therapy in Nigeria.
Malaria journal - 10 Nov 2021
Ikegbunam Moses, Ojo Johnson A, Kokou Kossiwa, Morikwe Ugonna, Nworu Chukwuemeka, Uba Chibuzo, Esimone Charles, Velavan Thirumalaisamy P, Ojurongbe Olusola
Abstract excerpt
BACKGROUND: The occurrence of artemisinin resistance (ART)-associated polymorphism of Plasmodium falciparum K13-propeller (pfk13) gene before and after the introduction of artemisinin-based combination therapy (ACT) in two regions of Nigeria was investigated in this study. Regular surveillance is necessary to make a definite conclusion on the emergence and pattern of possible resistance to ART. METHODS: This...
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