Article
Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study.
The Lancet. Microbe - 1 Sept 2021
Tumwebaze Patrick K, Katairo Thomas, Okitwi Martin, Byaruhanga Oswald, Orena Stephen, Asua Victor, Duvalsaint Marvin, Legac Jennifer, Chelebieva Sevil, Ceja Frida G, Rasmussen Stephanie A, Conrad Melissa D, Nsobya Samuel L, Aydemir Ozkan, Bailey Jeffrey A, Bayles Brett R, Rosenthal Philip J, Cooper Roland A
Abstract excerpt
BACKGROUND: Treatment and control of malaria depends on artemisinin-based combination therapies (ACTs) and is challenged by drug resistance, but thus far resistance to artemisinins and partner drugs has primarily occurred in southeast Asia. The aim of this study was to characterise antimalarial drug susceptibility of Plasmodium falciparum isolates from Tororo and Busia districts in Uganda. METHODS: In this...
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