Artemisinin-Resistant Plasmodium falciparum with High Survival Rates, Uganda, 2014-2016.

doi:10.3201/eid2404.170141

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Artemisinin-Resistant Plasmodium falciparum with High Survival Rates, Uganda, 2014-2016.

Emerging infectious diseases - 1 Apr 2018

Ikeda Mie, Kaneko Megumi, Tachibana Shin-Ichiro, Balikagala Betty, Sakurai-Yatsushiro Miki, Yatsushiro Shouki, Takahashi Nobuyuki, Yamauchi Masato, Sekihara Makoto, Hashimoto Muneaki, Katuro Osbert T, Olia Alex, Obwoya Paul S, Auma Mary A, Anywar Denis A, Odongo-Aginya Emmanuel I, Okello-Onen Joseph, Hirai Makoto, Ohashi Jun, Palacpac Nirianne M Q, Kataoka Masatoshi, Tsuboi Takafumi, Kimura Eisaku, Horii Toshihiro, Mita Toshihiro

Abstract excerpt

Because ≈90% of malaria cases occur in Africa, emergence of artemisinin-resistant Plasmodium falciparum in Africa poses a serious public health threat. To assess emergence of artemisinin-resistant parasites in Uganda during 2014-2016, we used the recently developed ex vivo ring-stage survival assay, which estimates ring-stage-specific P. falciparum susceptibility to artemisinin. We conducted 4 cross-sectional...

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Identifiers

PMID: 29553316
DOI: 10.3201/eid2404.170141
PMCID: PMC5875287

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