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Article

Genetic mutations in epigenetic modifiers as therapeutic targets in acute myeloid leukemia.

Expert opinion on therapeutic targets - 1 Jan 2015

Nebbioso Angela, Benedetti Rosaria, Conte Mariarosaria, Iside Concetta, Altucci Lucia

Abstract excerpt

INTRODUCTION: Despite enormous insights into the molecular mechanisms of acute myeloid leukemia (AML) pathophysiology, this disease is still fatal in the majority of patients, highlighting the urgent need for novel biomarkers useful in AML prognosis and therapy. AREAS COVERED: The advent of modern sequencing technologies has allowed the identification of genetic mutations in genes encoding for specific enzymes...

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Share to Antineoplastic Agents
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene Expression Regulation, Neoplastic

Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 26028314
DOI: 10.1517/14728222.2015.1051728

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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