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Article

Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia.

Blood - 2 May 2013

Abdel-Wahab Omar, Levine Ross L

Abstract excerpt

Recent studies of the spectrum of somatic genetic alterations in acute myeloid leukemia (AML) have identified frequent somatic mutations in genes that encode proteins important in the epigenetic regulation of gene transcription. This includes proteins involved in the modification of DNA cytosine residues and enzymes which catalyze posttranslational modifications of histones. Here we describe the clinical,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Epigenesis, Genetic

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Source

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Identifiers

PMID: 23640996
DOI: 10.1182/blood-2013-01-451781
PMCID: PMC3643757

Genes

ASXL1
IDH1
IDH2
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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