Article
CEBPA gene mutations in Egyptian acute myeloid leukemia patients: impact on prognosis.
Hematology (Amsterdam, Netherlands) - 1 Mar 2013
Awad Mohamed M, Aladle Doaa A, Abousamra Nashwa K, Elghannam Doaa M, Fawzy Iman M
Abstract excerpt
AIM: To assess the prognostic role of myeloid transcription factor gene CEBPA (CCAAT/enhancer binding protein-α), a novel gene involved in leukemia in Egyptian adults AML. MATERIALS AND METHODS: Screening for CEBPA mutations was assessed using PCR-single-strand conformation polymorphism (PCR-SSCP) in pretreatment bone marrow samples from 55 newly diagnosed adult AML. RESULTS: CEBPA mutations were found in 11...
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