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Article

Novel mutations in CEBPA in Korean Patients with acute myeloid leukemia with a normal karyotype.

Annals of laboratory medicine - 1 Mar 2012

Kim Sollip, Kim Dong-Hwan Dennis, Jang Jun-Ho, Jung Chul-Won, Jang Mi-Ae, Ki Chang-Seok, Kim Jong-Won, Kim Sun-Hee, Kim Hee-Jin

Abstract excerpt

Mutations in the transcription factor CCAAT/enhancer binding protein α gene (CEBPA) are found in 5-14% of the patients with AML and have been associated with a favorable clinical outcome. In this study, we aimed to assess the frequencies and characteristics of mutations in CEBPA. Between 2006 and 2009, CEBPA mutations were assessed using archival DNA samples obtained from 30 consecutive adult patients diagnosed...

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Identifiers

PMID: 22389883
DOI: 10.3343/alm.2012.32.2.153
PMCID: PMC3289781

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