Article
Xenopus TACC1 is a microtubule plus-end tracking protein that can regulate microtubule dynamics during embryonic development.
Cytoskeleton (Hoboken, N.J.) - 1 May 2015
Lucaj Christopher M, Evans Matthew F, Nwagbara Belinda U, Ebbert Patrick T, Baker Charlie C, Volk Joseph G, Francl Andrew F, Ruvolo Sean P, Lowery Laura Anne
Abstract excerpt
Microtubule plus-end dynamics are regulated by a family of proteins called plus-end tracking proteins (+TIPs). We recently demonstrated that the transforming acidic coiled-coil (TACC) domain family member, TACC3, can function as a +TIP to regulate microtubule dynamics in Xenopus laevis embryonic cells. Although it has been previously reported that TACC3 is the only TACC family member that exists in Xenopus, our...
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