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Article

Microtubule plus-end tracking proteins in neuronal development.

Cellular and molecular life sciences : CMLS - 1 May 2016

van de Willige Dieudonnée, Hoogenraad Casper C, Akhmanova Anna

Abstract excerpt

Regulation of the microtubule cytoskeleton is of pivotal importance for neuronal development and function. One such regulatory mechanism centers on microtubule plus-end tracking proteins (+TIPs): structurally and functionally diverse regulatory factors, which can form complex macromolecular assemblies at the growing microtubule plus-ends. +TIPs modulate important properties of microtubules including their...

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PMID: 26969328
DOI: 10.1007/s00018-016-2168-3
PMCID: PMC4834103

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