Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TACC3 Is Essential for EGF-Mediated EMT in Cervical Cancer

1 Aug 2013

Abstract excerpt

The third member of transforming acidic coiled-coil protein (TACC) family, TACC3, has been shown to be an important player in the regulation of centrosome/microtubule dynamics during mitosis and found to be deregulated in a variety of human malignancies. Our previous studies have suggested that TACC3 may be involved in cervical cancer progression and chemoresistance, and its overexpression can induce...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Cancer-related molecular mechanisms research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23936413
DOI: 10.1371/journal.pone.0070353

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TACC3 Is Essential for EGF-Mediated EMT in Cervical CancerPMID 23936413Read ↗

TACC3 transcriptionally upregulates E2F1 to promote cell growth and confer sensitivity to cisplatin in bladder cancer.Semantic proximity Read ↗

TACC3 promotes epithelial–mesenchymal transition (EMT) through the activation of PI3K/Akt and ERK signaling pathwaysSemantic proximity Read ↗

Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplificationSemantic proximity Read ↗

Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplificationSemantic proximity Read ↗

Abnormal TACC3 Expression is an Independent Prognostic Biomarker in Lung CarcinomaSemantic proximity Read ↗

Role of STAT3 in cancer cell epithelial‑mesenchymal transition (Review)Semantic proximity Read ↗

Novel therapeutic strategy for cervical cancer harboring FGFR3-TACC3 fusionsSemantic proximity Read ↗

Recurrent FGFR3-TACC3 fusion gene in nasopharyngeal carcinoma.Semantic proximity Read ↗

TUSC3 inhibits cell proliferation and invasion in cervical squamous cell carcinoma via suppression of the AKT signaling pathwaySemantic proximity Read ↗

A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling PathwaySemantic proximity Read ↗

ECT2 promotes malignant phenotypes through the activation of the AKT/mTOR pathway and cisplatin resistance in cervical cancer.Semantic proximity Read ↗

TTI-101 targets STAT3/c-Myc signaling pathway to suppress cervical cancer progression: an integrated experimental and computational analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.