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Article

Nrf2 inducer and cncC overexpression attenuates neurodegeneration due to α-synuclein in <i>Drosophila</i>

21 Apr 2015

Abstract excerpt

The study of the genes that are related to the pathogenesis of Parkinson's disease (PD) will improve our understanding of the mechanisms that underlie the development of PD. α-Synuclein is a major protein component of Lewy bodies, which are characteristic structures of PD pathology. Mutations in α-synuclein are closely related to the early onset of autosomal dominant PD. Transgenic flies with mutant α-synuclein...

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PMID: 26008822
DOI: 10.1139/bcb-2015-0015

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