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Article

The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans.

Metallomics : integrated biometal science - 1 Mar 2014

Bornhorst Julia, Chakraborty Sudipta, Meyer Sören, Lohren Hanna, Brinkhaus Sigrid Grosse, Knight Adam L, Caldwell Kim A, Caldwell Guy A, Karst Uwe, Schwerdtle Tanja, Bowman Aaron, Aschner Michael

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative brain disorder characterized by selective dopaminergic (DAergic) cell loss that results in overt motor and cognitive deficits. Current treatment options exist to combat PD symptomatology, but are unable to directly target its pathogenesis due to a lack of knowledge concerning its etiology. Several genes have been linked to PD, including three genes associated with...

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Identifiers

PMID: 24452053
DOI: 10.1039/c3mt00325f
PMCID: PMC3954834

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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