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Article

Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism.

Pharmacological research - 1 May 2011

Liu Zhaohui, Yu Yi, Li Xueping, Ross Christopher A, Smith Wanli W

Abstract excerpt

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder characterized by selective loss of dopaminergic neurons and the presence of Lewy bodies. The pathogenesis of PD remains incompletely understood, but it appears to involve both genetic susceptibility and environmental factors. Treatment for PD that prevents neuronal death in the dopaminergic system and abnormal protein deposition in the...

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PMID: 21237271
DOI: 10.1016/j.phrs.2011.01.004

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