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Article

Polymorphisms in ERCC1 and ERCC2/XPD genes and carcinogen DNA adducts in human lung.

Lung cancer (Amsterdam, Netherlands) - 1 Jul 2015

Lee Mi-Sun, Liu Chen-yu, Su Li, Christiani David C

Abstract excerpt

OBJECTIVES: In this exploratory study, we aimed to investigate whether polymorphisms in excision repair cross-complementing group 1 (ERCC1) and excision repair cross-complementing group 2/xeroderma pigmentosum group D (ERCC2/XPD) in the nucleotide excision repair (NER) pathways associated with DNA adducts in human lung tissue. We also analyzed the association stratified by the major histologic subtypes of...

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Source

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Identifiers

PMID: 26001533
DOI: 10.1016/j.lungcan.2015.05.001
PMCID: PMC4457615

Genes

ERCC2
ERCC1

Variants

rs3212986
rs3212986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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