Article
Association studies of ERCC1 polymorphisms with lung cancer susceptibility: a systematic review and meta-analysis.
PloS one - 1 Jan 2014
Zhu Jinhong, Hua Rui-Xi, Jiang Jing, Zhao Li-Qin, Sun Xiuwei, Luan Jinwei, Lang Yaoguo, Sun Yanqi, Shang Kun, Peng Shiyun, Ma Jianqun
Abstract excerpt
BACKGROUND: Excision repair cross-complimentary group 1 (ERCC1) is an essential component of the nucleotide excision repair system that is responsible for repairing damaged DNA. Functional genetic variations in the ERCC1 gene may alter DNA repair capacity and modulate cancer risk. The putative roles of ERCC1 gene polymorphisms in lung cancer susceptibility have been widely investigated. However, the results...
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