Article
Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.
Carcinogenesis - 1 Mar 2006
Zienolddiny Shanbeh, Campa Daniele, Lind Helge, Ryberg David, Skaug Vidar, Stangeland Lodve, Phillips David H, Canzian Federico, Haugen Aage
Abstract excerpt
Lung cancer is a leading cause of cancer mortality with an inter-individual difference in susceptibility to the disease. The inheritance of low-efficiency genotypes involved in DNA repair and replication may contribute to the difference in susceptibility. We investigated 44 single nucleotide polymorphisms (SNPs) in 20 DNA repair genes including nucleotide excision repair (NER) genes XPA, ERCC1, ERCC2/XPD,...
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