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Article

Polymorphisms in the DNA repair genes XRCC1 and ERCC2, smoking, and lung cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2003

Zhou Wei, Liu Geoffrey, Miller David P, Thurston Sally W, Xu Li Lian, Wain John C, Lynch Thomas J, Su Li, Christiani David C

Abstract excerpt

XRCC1 (X-ray cross-complementing group 1) and ERCC2 (excision repair cross-complementing group 2) are two major DNA repair proteins. Polymorphisms of these two genes have been associated with altered DNA repair capacity and cancer risk. We have described statistically significant interactions bet...

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Source

Identifiers

PMID: 12692111

Genes

ERCC2
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12692111-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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