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Article

Polymorphisms in excision repair cross-complementing group 4 (ERCC4) and susceptibility to primary lung cancer in a Chinese Han population.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 2008

Shao Minhua, Ma Hongxia, Wang Ying, Xu Liang, Yuan Jing, Wang Yi, Hu Zhibin, Yang Lin, Wang Feng, Liu Hongliang, Qian Ji, Xun Pengcheng, Chen Weihong, Yuan Wentao, Jing Guangfu, Chen Feng, Jin Li, Wei Qingyi, Wu Tangchun, Shen Hongbing, Huang Wei, Lu Daru

Abstract excerpt

ERCC4/XPF protein plays an important role in the nucleotide excision repair (NER) pathway, and deficiencies in the gene encoding it can lead to a repair-deficiency syndrome, xeroderma pigmentosum group F (XP-F). Common variants on this gene are assumed to be foreboding markers for lung cancer, and 4 selected SNPs in the ERCC4 gene were genotyped in a multi-center case-control study involving 1010 lung cancer...

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Identifiers

PMID: 18068852
DOI: 10.1016/j.lungcan.2007.10.023

Genes

ERCC4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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