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Article

CTLA4 and CD28 Gene Polymorphisms with Respect to Affective Symptom Domain in Schizophrenia.

Neuropsychobiology - 1 Jan 2015

Frydecka Dorota, Beszłej Jan Aleksander, Pawlak-Adamska Edyta, Misiak Błażej, Karabon Lidia, Tomkiewicz Anna, Partyka Anna, Jonkisz Anna, Szewczuk-Bogusławska Monika, Zawadzki Marcin, Kiejna Andrzej

Abstract excerpt

BACKGROUND: Accumulating evidence indicates that immune alterations in schizophrenia are due to genetic underpinnings. Here, we aimed at investigating whether polymorphisms in CTLA4 and CD28 genes, encoding molecules that regulate T-cell activity, influence schizophrenia symptomatology. METHOD: We recruited 120 schizophrenia patients and 380 healthy age- and sex-matched controls. We divided the patients into two...

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Source

Identifiers

PMID: 25998553
DOI: 10.1159/000379751

Genes

CTLA4

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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