Association between genetic variants of TLR2, TLR4, TLR9 and schizophrenia.

doi:10.1016/j.encep.2023.05.004

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Article

Association between genetic variants of TLR2, TLR4, TLR9 and schizophrenia.

L'Encephale - 1 Apr 2024

Ayari Fayza, Chaaben Arij Ben, Abaza Hajer, Mihoub Ons, Ouni Nesrine, Boukouaci Wahid, Kharrat Maher, Leboyer Marion, Guemira Fethi, Tamouza Ryad, Mankai Amani

Abstract excerpt

BACKGROUND AND STUDY AIM: Schizophrenia (SZ) is a multifactorial disorder involving complex interactions between genetic and environmental factors, where immune dysfunction plays a key etiopathogenic role. In order to explore the control of innate immune responses in SZ, we aimed to investigate the potential association between twelve TLR2, TLR4 and TLR9 variants (TLR2: rs4696480T>A, rs3804099T>C, rs3804100T>C;...

Topics

Humans
Toll-Like Receptor 2
Toll-Like Receptor 4
Toll-Like Receptor 9
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide
Schizophrenia
Genotype
Case-Control Studies

Source

Open in PubMed

Identifiers

PMID: 37718198
DOI: 10.1016/j.encep.2023.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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