Article
Association study of interleukin-4 polymorphisms with paranoid schizophrenia in the Polish population: a critical approach.
Molecular biology reports - 1 Aug 2012
Fila-Danilow Anna, Kucia Krzysztof, Kowalczyk Malgorzata, Owczarek Aleksander, Paul-Samojedny Monika, Borkowska Paulina, Suchanek Renata, Kowalski Jan
Abstract excerpt
Changes in immunological system are one of dysfunctions reported in schizophrenia. Some changes based on an imbalance between Th1 and Th2 cytokines results from cytokine gene polymorphisms. Interleukin-4 gene (IL4) is considered as a potential candidate gene in schizophrenia association studies....
Topics
- Adult
- Aged
- Alleles
- Analysis of Variance
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-4
- Linkage Disequilibrium
- Male
- Middle Aged
- Poland
- Polymorphism, Single Nucleotide