Article
Association of tumor necrosis factor -308G/A promoter polymorphism with schizophrenia and bipolar affective disorder in a Polish population.
Neuropsychobiology - 1 Jan 2008
Czerski Piotr M, Rybakowski Filip, Kapelski Paweł, Rybakowski Janusz K, Dmitrzak-Weglarz Monika, Leszczyńska-Rodziewicz Anna, Słopień Agnieszka, Skibińska Maria, Kaczmarkiewicz-Fass Magdalena, Hauser Joanna
Abstract excerpt
BACKGROUND/AIMS: Schizophrenia (SCH) and bipolar affective disorder (BPAD) are complex disorders with significant participation of genetic risk factors. Several lines of evidence point to the role of shared neurobiological mechanisms and common genetic background in SCH and BPAD. Immune disturbances have been suggested as contributing factor in the pathogenesis of both SCH and BPAD. The gene coding cytokine tumor...
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