Article
IL-28B genetic variant is associated with the risk of schizophrenia in the Chinese Han population.
DNA and cell biology - 1 Jun 2012
Chen Chunxia, Tan Bin, Zhou Yi, Zhou Juan, He Yong, Li Siyue, Ying Binwu, Qin Li
Abstract excerpt
Schizophrenia is a severe psychiatric disorder. Although its exact cause is unknown, it is widely accepted that environmental factors and genes integrate in the pathogenesis of schizophrenia. 19q13, which contains IL-28B, is a newly identified potential susceptibility locus. IL-28B is a cytokine that functionally has anti-viral activity, but, structurally, is related to the interleukin-10 family. Both virus...
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