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Article

Polymorphisms in immune-inflammatory response genes and the risk of deficit schizophrenia.

Schizophrenia research - 1 Mar 2018

Mak Monika, Misiak Błażej, Frydecka Dorota, Pełka-Wysiecka Justyna, Kucharska-Mazur Jolanta, Samochowiec Agnieszka, Bieńkowski Przemysław, Pawlak-Adamska Edyta, Karabon Lidia, Szmida Elżbieta, Skiba Paweł, Kotowicz Kamila, Piotrowski Patryk, Beszłej Jan Aleksander, Samochowiec Jerzy

Abstract excerpt

Polymorphisms in immune-inflammatory response genes are believed to impact schizophrenia susceptibility. However, it remains unknown whether immunogenetic factors play a role in the etiology of deficit schizophrenia (D-SCZ). Therefore, we genotyped four polymorphisms in genes encoding two immune system regulatory proteins (CTLA-4 rs231775 and CD28 rs3116496), interleukin-6 (IL6 rs1800795) and transforming growth...

Topics

Adult
CD28 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

CTLA-4 Antigen

Cytokines

Female

Gene Frequency

Genetic Predisposition to Disease

Genotype

Humans

Male

Middle Aged

Polymorphism, Single Nucleotide

Schizophrenia

Transforming Growth Factor beta

Source

Identifiers

PMID: 28673752
DOI: 10.1016/j.schres.2017.06.050

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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