Article
Analysis of sphingosine-1-phosphate signaling mutants reveals endodermal requirements for the growth but not dorsoventral patterning of jaw skeletal precursors.
Developmental biology - 15 Feb 2012
Balczerski Bartosz, Matsutani Megan, Castillo Pablo, Osborne Nick, Stainier Didier Y R, Crump J Gage
Abstract excerpt
Development of the head skeleton involves reciprocal interactions between cranial neural crest cells (CNCCs) and the surrounding pharyngeal endoderm and ectoderm. Whereas elegant experiments in avians have shown a prominent role for the endoderm in facial skeleton development, the relative functions of the endoderm in growth versus regional identity of skeletal precursors have remained unclear. Here we describe...
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