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Article

Effects of phenotypic and genotypic factors on the lipid responses to niacin in Chinese patients with dyslipidemia.

Medicine - 1 May 2015

Hu Miao, Yang Ya-Ling, Ng Chi-Fai, Lee Chui-Ping, Lee Vivian W Y, Hanada Hiroyuki, Masuda Daisaku, Yamashita Shizuya, Tomlinson Brian

Abstract excerpt

The acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes DGAT1 and DGAT2 catalyze the final step in triglycerides biosynthesis. This study examined the relationships of baseline phenotypes and the common polymorphisms in DGAT1 and DGAT2 with the lipid responses to niacin.Lipid responses in Chinese patients with dyslipidemia treated with the extended release (ER) niacin/laropiprant combination 1000/20 mg for 4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25997070
DOI: 10.1097/MD.0000000000000881
PMCID: PMC4602879

Genes

DGAT2
DGAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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