Article
Interactions among genes involved in reverse cholesterol transport and in the response to environmental factors in dyslipidemia in subjects from the Xinjiang rural area.
PloS one - 1 Jan 2018
Wang Xinping, Guo Heng, Li Yu, Wang Haixia, He Jia, Mu Lati, Hu Yunhua, Ma Jiaolong, Yan Yizhong, Li Shugang, Ding Yusong, Zhang Mei, Niu Qiang, Liu Jiaming, Zhang Jingyu, Ma Rulin, Guo Shuxia
Abstract excerpt
Gene-gene and gene-environment interactions may be partially responsible for dyslipidemia, but studies investigating interactions in the reverse cholesterol transport system (RCT) are limited. We explored these interactions in a Xinjiang rural population by genotyping five SNPs using SNPShot technique in APOA1, ABCA1, and LCAT, which are involved in the RCT (690 patients, 743 controls). We conducted unconditional...
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