Article
The effect of sterol regulatory element-binding protein 2 polymorphism on the serum lipid in northern Chinese subjects.
Journal of lipid research - 1 Feb 2005
Duan Xueying, Zhu Wenli, Li Yong, Zhang Zhentao, Zhao Yao, Dao Jingjing, Xiao Ying
Abstract excerpt
Sterol regulatory element-binding protein 2 (SREBP-2) is an important nuclear transcription factor in the regulation of cellular cholesterol metabolism. To determine allele frequency of the 1784G>C polymorphism at the SREBP-2 locus and investigate the relationship between this polymorphism and serum lipid levels in Chinese people, we selected 486 individuals (118 men and 368 women) from the Xicheng District of...
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