Article
Efficacy of habitual exercise for improving lipid profiles depends on the PPRAγ genotype in Japanese males.
Journal of nutritional science and vitaminology - 1 Jan 2014
Sone Yasuko, Hirasawa Reiko, Ichi Ikuyo, Ishikawa Tomoko, Kodama Satoru, Sone Hirohito, Egawa Shigenobu, Kawahara Kazuo, Otsuka Yuzuru, Fujiwara Yoko
Abstract excerpt
Peroxisome proliferator-activated receptor gamma (PPARγ) responds to thiazolidinedione derivatives, which are ligands of PPARγ, and affects insulin resistance. Recently, a PPARγ study reported that in high-fat-diet-induced obesity, the phosphorylation of PPARγ prevented the transcription of specific PPARγ targets that have anti-obesity effects. We previously reported that genetic variants of the fatty acid...
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