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Article

Liver fat reduction with niacin is influenced by DGAT-2 polymorphisms in hypertriglyceridemic patients.

Journal of lipid research - 1 Apr 2012

Hu Miao, Chu Winnie Chiu Wing, Yamashita Shizuya, Yeung David Ka Wai, Shi Lin, Wang Defeng, Masuda Daisaku, Yang Yaling, Tomlinson Brian

Abstract excerpt

Niacin reduces plasma triglycerides, but it may increase free fatty acids and insulin resistance during long-term treatment. We examined the effect of extended-release niacin on liver fat content in Chinese patients with dyslipidemia and whether the common diacylglycerol acyltransferase-2 (DGAT2) polymorphisms influenced this effect. The 39 patients (baseline liver fat content: 12.8 ± 7.6%, triglycerides: 3.30 ±...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22315393
DOI: 10.1194/jlr.P023614
PMCID: PMC3307657

Genes

DGAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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