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Article

Role of CYP2D6 Polymorphisms in the Outcome of Postoperative Pain Treatment.

Pain medicine (Malden, Mass.) - 1 Oct 2015

Seripa Davide, Latina Paola, Fontana Andrea, Gravina Carolina, Lattanzi Monia, Savino Maria, Gallo Antonietta P, Melchionda Giuseppe, Santini Stefano A, Margaglione Maurizio, Copetti Massimiliano, di Mauro Lazzaro, Panza Francesco, Greco Antonio, Pilotto Alberto

Abstract excerpt

OBJECTIVE: To investigate the role of CYP2D6 phenotype in the outcome of postoperative (PO) pain (POP) treatment. DESIGN: Longitudinal cohort study. Open-label trial with post hoc analysis. SETTING: General Hospital Surgery and Recovery Units. PATIENTS: Ninety unrelated Caucasians submitted to abdominal/thoracic surgery. INTERVENTIONS: Standard multimodal POP treatment including opioids (tramadol) and...

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Identifiers

PMID: 25989235
DOI: 10.1111/pme.12778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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