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Article

Mouse model of OPRM1 (A118G) polymorphism has altered hippocampal function.

Neuropharmacology - 1 Oct 2015

Mague Stephen D, Port Russell G, McMullen Michael E, Carlson Greg C, Turner Jill R

Abstract excerpt

A single nucleotide polymorphism (SNP) in the human μ-opioid receptor gene (OPRM1 A118G) has been widely studied for its association in a variety of drug addiction and pain sensitivity phenotypes; however, the extent of these adaptations and the mechanisms underlying these associations remain elusive. To clarify the functional mechanisms linking the OPRM1 A118G SNP to altered phenotypes, we used a mouse model...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 25986698
DOI: 10.1016/j.neuropharm.2015.04.032
PMCID: PMC4536923

Genes

OPRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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