A polymorphism in CCR1/CCR3 is associated with narcolepsy.

doi:10.1016/j.bbi.2015.05.003

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A polymorphism in CCR1/CCR3 is associated with narcolepsy.

Brain, behavior, and immunity - 1 Oct 2015

Toyoda Hiromi, Miyagawa Taku, Koike Asako, Kanbayashi Takashi, Imanishi Aya, Sagawa Yohei, Kotorii Nozomu, Kotorii Tatayu, Hashizume Yuji, Ogi Kimihiro, Hiejima Hiroshi, Kamei Yuichi, Hida Akiko, Miyamoto Masayuki, Imai Makoto, Fujimura Yota, Tamura Yoshiyuki, Ikegami Azusa, Wada Yamato, Moriya Shunpei, Furuya Hirokazu, Takeuchi Masaki, Kirino Yohei, Meguro Akira, Remmers Elaine F, Kawamura Yoshiya, Otowa Takeshi, Miyashita Akinori, Kashiwase Koichi, Khor Seik-Soon, Yamasaki Maria, Kuwano Ryozo, Sasaki Tsukasa, Ishigooka Jun, Kuroda Kenji, Kume Kazuhiko, Chiba Shigeru, Yamada Naoto, Okawa Masako, Hirata Koichi, Mizuki Nobuhisa, Uchimura Naohisa, Shimizu Tetsuo, Inoue Yuichi, Honda Yutaka, Mishima Kazuo, Honda Makoto, Tokunaga Katsushi

Abstract excerpt

Etiology of narcolepsy-cataplexy involves multiple genetic and environmental factors. While the human leukocyte antigen (HLA)-DRB1*15:01-DQB1*06:02 haplotype is strongly associated with narcolepsy, it is not sufficient for disease development. To identify additional, non-HLA susceptibility genes, we conducted a genome-wide association study (GWAS) using Japanese samples. An initial sample set comprising 409 cases...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Asian People

Share to CCR1 gene

Share to CCR3 gene

Share to Genome-Wide Association Study

Share to Japan

Share to Narcolepsy

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 25986216
DOI: 10.1016/j.bbi.2015.05.003

Genes

CCR1
CCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A polymorphism in CCR1/CCR3 is associated with narcolepsy.PMID 25986216Read ↗

HLA-DQB1*03:01 strongly affects age of onset of type 1 narcolepsy independently of DQA1 and ethnicity.Semantic proximity Read ↗

Epigenome-wide association study of DNA methylation in narcolepsy: an integrated genetic and epigenetic approach.Semantic proximity Read ↗

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy.Semantic proximity Read ↗

Identification of the variations in the CPT1B and CHKB genes along with the HLA-DQB1*06:02 allele in Turkish narcolepsy patients and healthy persons.Semantic proximity Read ↗

Genomewide association analysis of human narcolepsy and a new resistance gene.Semantic proximity Read ↗

HLA-DQB1*03:01 strongly affects age of onset of type 1 narcolepsy independently of DQA1 and ethnicitySemantic proximity Read ↗

TCRA, P2RY11, and CPT1B/CHKB associations in Chinese narcolepsy.Semantic proximity Read ↗

New susceptibility variants to narcolepsy identified in HLA class II region.Semantic proximity Read ↗

DQB1*0301 and DQB1*0601 modulate narcolepsy susceptibility in Koreans.Semantic proximity Read ↗

The epidemiology of narcolepsy.Semantic proximity Read ↗

High-resolution HLA sequencing and hypocretin receptor 2 autoantibodies in narcolepsy type 1 and type 2.Semantic proximity Read ↗

DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.