Article
Genomewide association analysis of human narcolepsy and a new resistance gene.
American journal of human genetics - 1 Aug 2006
Kawashima Minae, Tamiya Gen, Oka Akira, Hohjoh Hirohiko, Juji Takeo, Ebisawa Takashi, Honda Yutaka, Inoko Hidetoshi, Tokunaga Katsushi
Abstract excerpt
Human narcolepsy is a hypersomnia that is affected by multiple genetic and environmental factors. One genetic factor strongly associated with narcolepsy is the HLA-DRB1*1501-DQB1*0602 haplotype in the human leukocyte antigen region on chromosome 6, whereas the other genetic factors are not clear. To discover additional candidate regions for susceptibility or resistance to human narcolepsy, we performed a...
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