Article
The polymorphic terminal-loop of pre-miR-1307 binding with MBNL1 contributes to colorectal carcinogenesis via interference with Dicer1 recruitment.
Carcinogenesis - 1 Aug 2015
Tang Rong, Qi Qinghua, Wu Ruirong, Zhou Xinru, Wu Dongjuan, Zhou Huan, Mao Yong, Li Rui, Liu Cuiping, Wang Lei, Chen Weichang, Hua Dong, Zhang Hongjian, Wang Weipeng
Abstract excerpt
Colorectal cancer (CRC) is one of the most common malignancies in the world. Studies have demonstrated that single nucleotide polymorphisms (SNPs) in microRNA genes (miRSNPs) are involved in the occurrence of cancers. However, the relationship between the miRSNPs within the terminal-loops of microRNA precursors and the development of CRC is still largely unknown. In this study, we found that a miRSNP rs7911488...
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