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Article

A functional polymorphism in lnc-LAMC2-1:1 confers risk of colorectal cancer by affecting miRNA binding.

Carcinogenesis - 1 May 2016

Gong Jing, Tian Jianbo, Lou Jiao, Ke Juntao, Li Lu, Li Jiaoyuan, Yang Yang, Gong Yajie, Zhu Ying, Zhang Yi, Zhong Rong, Chang Jiang, Miao Xiaoping

Abstract excerpt

Genome-wide association studies (GWASs) have identified multiple susceptibility loci of colorectal cancer (CRC), however, causative polymorphisms have not been fully elucidated. Long non-coding RNAs (lncRNAs) are a recently discovered class of non-protein coding RNAs that involved in a wide variety of biological processes. We hypothesized that single nucleotide polymorphisms (SNPs) in lncRNA may associate with...

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Identifiers

PMID: 26905585
DOI: 10.1093/carcin/bgw024

Genes

LAMC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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