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Article

Genetic variants in miRNA processing genes and pre-miRNAs are associated with the risk of chronic lymphocytic leukemia.

PloS one - 1 Jan 2015

Martin-Guerrero Idoia, Gutierrez-Camino Angela, Lopez-Lopez Elixabet, Bilbao-Aldaiturriaga Nerea, Pombar-Gomez Maria, Ardanaz Maite, Garcia-Orad Africa

Abstract excerpt

Genome wide association studies (GWAS) have identified several low-penetrance susceptibility alleles in chronic lymphocytic leukemia (CLL). Nevertheless, these studies scarcely study regions that are implicated in non-coding molecules such as microRNAs (miRNAs). Abnormalities in miRNAs, as altered expression patterns and mutations, have been described in CLL, suggesting their implication in the development of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Share to Nucleic Acid Conformation

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Share to RNA Processing, Post-Transcriptional

Source

Open in PubMed Open full text

Identifiers

PMID: 25793711
DOI: 10.1371/journal.pone.0118905
PMCID: PMC4368096

Genes

CNOT1
DICER1
DROSHA
SND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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