Article

Tumor Suppression across the Human miRNome Associates with Guanine-Rich Precursor Terminal Loops

2026-01-27

Abstract excerpt

MicroRNAs (miRNAs) play essential regulatory roles in controlling cell growth, proliferation, and differentiation in cancer. While functional studies have identified numerous oncogenic (oncomiRs) and tumor suppressor (TS) miRNAs, the structural features that differentiate these groups remain poorly understood. Here, we performed a comprehensive sequence analysis of 955 human pre-miRNA terminal loops (TLs), focusin...

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Literature Corpus work: ef59b8d1-eabd-5c5a-a431-c093903533fe
DOI: 10.64898/2026.01.26.701701

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