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Article

Polymorphism rs2682818 in miR-618 is associated with colorectal cancer susceptibility in a Han Chinese population.

Cancer medicine - 1 Apr 2018

Chen Yuetong, Du Mulong, Chen Wei, Zhu Lingjun, Wu Congye, Zhang Zhengdong, Wang Meilin, Chu Haiyan, Gu Dongying, Chen Jinfei

Abstract excerpt

MicroRNAs (miRNAs), endogenous small noncoding RNAs (ncRNAs), play crucial roles in cancer development. Many studies have demonstrated that miRNAs can serve as diagnostic and therapeutic biomarkers for malignancies. Additionally, single nucleotide polymorphisms (SNPs) located in miRNA functional regions have been reported to be involved in cancer susceptibility. In this study, we investigated the associations...

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PMID: 29533012
DOI: 10.1002/cam4.1409
PMCID: PMC5911622

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