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Article

Involvement of the HCK and FGR src-family kinases in FCRL4-mediated immune regulation.

Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2015

Liu Yanling, Bezverbnaya Ksenia, Zhao Tiantian, Parsons Marion J, Shi Mengyao, Treanor Bebhinn, Ehrhardt Götz R A

Abstract excerpt

FCRL4 is an immunoregulatory receptor expressed by a subpopulation of memory B cells. These tissue-based cells express increased levels of the src-family kinases HCK and FGR. In this study, we investigate the roles of these src-family kinases in FCRL4-mediated immunoregulation of B cells in the context of previously unrecognized palmitoylation of the receptor. We observed enhanced phosphorylation of FCRL4 on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25972488
DOI: 10.4049/jimmunol.1401533
PMCID: PMC4456631

Genes

FCRL4
FGR
HCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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