Article
The inhibitory potential of Fc receptor homolog 4 on memory B cells.
Proceedings of the National Academy of Sciences of the United States of America - 11 Nov 2003
Ehrhardt Gotz R A, Davis Randall S, Hsu Joyce T, Leu Chuen-Miin, Ehrhardt Annette, Cooper Max D
Abstract excerpt
Fc receptor homolog 4 (FcRH4) is a B cell-specific member of the recently identified family of FcRHs whose intracellular domain contains three potential immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The signaling potential of this receptor, shown here to be preferentially expressed by memory B cells, was compared with the inhibitory receptor FcgammaRIIb in B cells expressing either WT FcgammaRIIb or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.