Article
Type II phosphatidylinositol 4-kinases interact with FcεRIγ subunit in RBL-2H3 cells.
Molecular and cellular biochemistry - 1 May 2014
Bojjireddy Naveen, Sinha Ranjeet Kumar, Subrahmanyam Gosukonda
Abstract excerpt
Ligation of high-affinity IgE receptor I (FcεRI) on RBL-2H3 cells leads to recruitment of FcεRI and type II phosphatidylinositol 4-kinases (PtdIns 4-kinases) into lipid rafts. Lipid raft integrity is required for the activation of type II PtdIns 4-kinases and signal transduction through FcεRIγ during RBL-2H3 cell activation. However, the molecular mechanism by which PtdIns 4-kinases are coupled to FcεRI signaling...
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