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Article

Multilocus heterozygosity and coronary heart disease: nested case-control studies in men and women.

PloS one - 1 Jan 2015

Mukamal Kenneth J, Jensen Majken K, Pers Tune H, Pai Jennifer K, Kraft Peter, Rimm Eric B

Abstract excerpt

BACKGROUND: Generalized allelic heterozygosity has been proposed to improve reproductive fitness and has been associated with higher blood pressure, but its association with chronic disease is not well characterized. METHODS: Using the Affymetrix Genome-Wide Human 6.0 array, we performed whole genome scans in parallel case-control studies of coronary heart disease (CHD) nested in the Health Professionals...

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Identifiers

PMID: 25970579
DOI: 10.1371/journal.pone.0124847
PMCID: PMC4430477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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