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Article

Association between SNP heterozygosity and quantitative traits in the Framingham Heart Study.

Annals of human genetics - 1 Jul 2009

Govindaraju Didahally R, Larson Martin G, Yin Xiaoyan, Benjamin Emelia J, Rao Marepalli B, Vasan Ramachandran S

Abstract excerpt

Associations between multilocus heterozygosity and fitness traits, also termed heterozygosity and fitness correlations (HFCs), have been reported in numerous organisms. These studies, in general, indicate a positive relationship between heterozygosity and fitness traits. We studied the association between genome-wide heterozygosity at 706 non-synonymous and synonymous SNPs and 19 quantitative traits, including...

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Identifiers

PMID: 19523151
DOI: 10.1111/j.1469-1809.2009.00514.x
PMCID: PMC3760672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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