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Article

Haptoglobin genotype is a consistent marker of coronary heart disease risk among individuals with elevated glycosylated hemoglobin.

Journal of the American College of Cardiology - 19 Feb 2013

Cahill Leah E, Levy Andrew P, Chiuve Stephanie E, Jensen Majken K, Wang Hong, Shara Nawar M, Blum Shany, Howard Barbara V, Pai Jennifer K, Mukamal Kenneth J, Rexrode Kathryn M, Rimm Eric B

Abstract excerpt

OBJECTIVES: This study sought to investigate into the biologically plausible interaction between the common haptoglobin (Hp) polymorphism rs#72294371 and glycosylated hemoglobin (HbA(1c)) on risk of coronary heart disease (CHD). BACKGROUND: Studies of the association between the Hp polymorphism and CHD report inconsistent results. Individuals with the Hp2-2 genotype produce Hp proteins with an impaired ability to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23312704
DOI: 10.1016/j.jacc.2012.09.063
PMCID: PMC3678553

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